Adalimumab in juvenile idiopathic arthritis-associated chronic anterior uveitis
نویسندگان
چکیده
منابع مشابه
Adalimumab in juvenile idiopathic arthritis-associated chronic anterior uveitis.
OBJECTIVE To evaluate the efficacy of adalimumab in juvenile idiopathic arthritis (JIA)-associated uveitis. METHODS Retrospective observational study of 20 patients with JIA and chronic uveitis on adalimumab treatment. The ocular inflammation and improvement was assessed according to the Standardization of Uveitis Nomenclature criteria. RESULTS At the initiation of adalimumab, the mean age ...
متن کاملJuvenile idiopathic arthritis-associated uveitis
Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease of childhood, with JIA-associated uveitis its most common extra-articular manifestation. JIA-associated uveitis is a potentially sight-threatening condition and thus carries a considerable risk of morbidity. The aetiology of the condition is autoimmune in nature with the predominant involvement of CD4(+) T cells. However, ...
متن کاملJuvenile Idiopathic Arthritis associated uveitis
Systemic JIA represents 20% of all JIA cases. It is characterized by the onset of high-grade fever associated with multiple extra-articular manifestations. [2] These include maculopapular rash, generalized lymphadenopathy, hepatomegaly, splenomegaly, pericarditis, and pleuritis. Joint involvement is initially mild or absent, but becomes the more prominent feature of the disease as the patient a...
متن کاملAdalimumab and severe uveitis in juvenile idiopathic arthritis (JIA) therapy
Results When Enbrel plus Methotrexate was started she got into remission. After one year of this therapy, she presented uveitis in both eyes, so oral steroids were started again. She obtained only partial ocular improvement, even when she received Infliximab associated with Methotrexate. Meantime she underwent cataract surgery with visus reduction. After one year, Infliximab was suspended becau...
متن کاملAnti-adalimumab antibodies in juvenile idiopathic arthritis-related uveitis.
OBJECTIVES To evaluate the association of adalimumab trough levels and anti-adalimumab antibodies with activity of uveitis in juvenile idiopathic arthritis-related uveitis. METHODS This was a retrospective observational case series in a clinical setting at the Department of Ophthalmology, Helsinki University Hospital, Finland in 2014-2016. Thirty-one paediatric patients with chronic anterior ...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2007
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/kem356